Interaction | Reaction | Process     Data Page

Primary amines react with chloroform in the presence of base (strong aq. NaOH) to yield isocyanides.

R–NH2
  +  
CHCl3
  +  
Base
Proton abstractor
         
R–NC
Reactant Page Go To Go To
1° Amine (generic)     Reactions Using    Reactions Forming
Chloroform     Reactions Using    Reactions Forming
Base, charged (generic)     Reactions Using    Reactions Forming
Isocyanide (generic)     Reactions Using    Reactions Forming

Interaction, Reaction, Process defined as:
Multistep: LA/B mechanism

© Mark R. Leach 1999 –


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