Interaction | Reaction | Process     Data Page

Acid chlorides are partially reduced to aldehydes with lithium tri-tert-butoxyaluminium hydride.

The mechanism is likely to involve nucleophilic hydride ion. This mehod is equivalent to the Rosenmund reduction.

Generic Organic reaction
RCOCl
  +  
Li[Al(OtBu)3H]
1.0M in THF
  +  
         
RCHO
Reactant Page Go To Go To
Acid chloride (generic)     Reactions Using    Reactions Forming
Lithium tri-tert-butoxy aluminium hydride     Reactions Using    Reactions Forming
Diethylether Solvent    Reactions Using    Reactions Forming
Aldehyde (generic)     Reactions Using    Reactions Forming

Interaction, Reaction, Process defined as:
Functional Group Interconvertion
Reduction: Of Substrate By Reagent
Substitution: Addition-followed-by Elimination
Substitution: Nucleophilic @ Acyl-Nfg

© Mark R. Leach 1999 –

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