|Interactions, reactions or processes classified as:|
The benzyne mechanism is a type of strong base catalysed elimination-followed-by-addition aromatic substitution. A strong base, often NH2- in NH3, abstracts a proton which initiates the ejection of a nucleofuge so forming a highly reactive "benzyne", a type of highly strained alkyne. The benzyne reactive intermediate is highly susceptible to nucleophilic addition. Benzyne reaction products show characteristic substitution patterns.