Interaction | Reaction | Process     Data Page

para-Nitroacetamide is alpha-brominated with bromine in glacial acetic acid. (The enol form of the ketone attacks the Br2 ejecting bromide ion.)

The Chemistry of the Antibiotics used in Medicine, R.M Evans, The Commonwealth and International Library of Science Technology Engineering and Liberal Studies.
  +  
Br2
  +  
CH3COOH
         
  +  
HBr
Reactant Page Go To Go To
4-Nitroacetophenone     Reactions Using    Reactions Forming
Bromine     Reactions Using    Reactions Forming
Acetic acid Solvent    Reactions Using    Reactions Forming
2-Bromo-1-(4-nitrophenyl)ethanone     Reactions Using    Reactions Forming
Hydrogen bromide     Reactions Using    Reactions Forming

Interaction, Reaction, Process defined as:
Substitution: Nucleophilic Second Order
Synthesis of Chloramphenicol
Tautomerism

© Mark R. Leach 1999 –

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