Interactions | Reactions | Processes


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Classified as: Substitution: Ingold's Four Types of Sn2



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Ingold performed an analysis of the effect of solvent upon four subclasses of Sn2 substitution, where sub-classification concerns the relative charges of the nucleophile and the nucleofuge.
CH3I
  +  
[OH]–
        
CH3OH
  +  
I–

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CH3I
  +  
(CH3)3N
        
[(CH3)4N]+
  +  
I–

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[(CH3)4N]+
  +  
[OH]–
        
CH3OH
  +  
(CH3)3N

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[(CH3)4N]+
  +  
H2S
        
[CH3–SH2]+
  +  
(CH3)3N

Go To Reaction Data Page

© Mark R. Leach 1999 –

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