Interactions | Reactions | Processes

Classified as: Substitution: Ingold's Four Types of Sn2

Ingold performed an analysis of the effect of solvent upon four subclasses of Sn2 substitution, where sub-classification concerns the relative charges of the nucleophile and the nucleofuge.
CH3I
  +  
[OH]–
         
CH3OH
  +  
I–

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CH3I
  +  
(CH3)3N
         
[(CH3)4N]+
  +  
I–

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[(CH3)4N]+
  +  
[OH]–
         
CH3OH
  +  
(CH3)3N

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[(CH3)4N]+
  +  
H2S
         
[CH3–SH2]+
  +  
(CH3)3N

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© Mark R. Leach 1999 –

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